GH10 xylanase D from Penicillium funiculosum: biochemical studies and xylooligosaccharide production

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GH10 xylanase D from Penicillium funiculosum: biochemical studies and xylooligosaccharide production

BACKGROUND The filamentous fungus Penicillium funiculosum produces a range of glycoside hydrolases (GH). The XynD gene, encoding the sole P. funiculosum GH10 xylanase described so far, was cloned into the pPICZαA vector and expressed in methylotrophe yeast Pichia pastoris, in order to compare the results obtained with the P. funiculosum GH11 xylanases data. RESULTS High level expression of re...

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Recently, xylanases have expanded their use in many processing industries, such as pulp and paper, food and textile. The production of xylanase by the fungus Penicillium sclerotiorum under submerse cultivation was investigated. Oat spelts xylan and wheat bran were the best inducers of xylanase activity. Optimal xylanase production was obtained in liquid Vogel medium, pH 6.5, at 30oC, under stat...

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The Aspergillus niger xylanase (Xyn) was used as a model to investigate impacts of un-structured residues on GH11 family enzyme, because the β-jelly roll structure has five residues (Ser1Ala2Gly3Ile4Asn5) at N-terminus and two residues (Ser183Ser184) at C-terminus that do not form to helix or strand. The N- or/and C-terminal residues were respectively deleted to construct three mutants. The opt...

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ژورنال

عنوان ژورنال: Microbial Cell Factories

سال: 2011

ISSN: 1475-2859

DOI: 10.1186/1475-2859-10-20